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Etoricoxib beta 90 mg wirkstoff, 40 voriconazole, 75 ketoconazole) or metronidazole (90 mg twice daily) to achieve complete removal of P. gingivalis. Cigarette smoking is not considered to cause any direct harm people whose breath is tested for bacteria and the study was not designed to exclude the effects of this. As the main method of elimination may not be effective and the drug will not be removed entirely from the patient's body this may also limit a successful clinical trial of tetracycline or another anti-gingival antibiotic. The researchers say their findings could lead to new ways of treating patients infected with P. gingivalis. These include the use of tetracycline as an anti-gingirial, and new ways of treating the bacteria directly - using antibiotics. Dr Pauline Hickey from the University of Sheffield said: "We found the drug could inhibit growth of P. gingivalis on lung tissue. "But these bacteria are quite robust and do not usually survive being removed from the mouth. We have shown that it can also Is diazepam generic for valium inhibit the growth on mucosal lining of the throat. "This may enable us to develop a long-term treatment for this difficult to treat condition, without the need for antibiotics which are more widely required by people with gum disease." The study involved 50 people suffering from gum disease. Participants were given either 2.5g (250 mg) of oral tetracycline for 14 days or a placebo. Their gut and other organs were examined at the end of treatment and another three months after the 14 day course was given. The researchers say oral tetracycline can also kill all of the bacteria normally residing in gastrointestinal tract. They were concerned however that patients who could not tolerate the drug or could not maintain the required dose over necessary 14 days would not have been included in the study. Professor Andrew Cramer, of Queen Mary University, said: "Our study is interesting because the drug appears to not only kill the main organisms causing infections in gums the mouth but may also remove P. gingivalis spores, too. "This study shows that we may have a new therapy for chronic gum disease patients. "We hope that this will allow us to develop more effective drugs that can be given to patients who would need more than 14 days of treatment to kill P. gingivalis. "Gums can be very painful, so a longer cure for gingivitis can be very attractive."
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